Guadagnare Salute

Epidemiologia e prevenzione delle malattie cerebro e cardiovascolari



The MORGAM Project


The MORGAM (MOnica Risk, Genetics, Archiving and Monograph) Project is a multinational collaborative study exploring the relationships between the development of cardiovascular diseases, their classic and genetic risk factors and biomarkers. This is done through follow-up of cohorts examined in the MONICA risk factor surveys and other studies.


In the 2000s, the MORGAM project cohorts became part of the following projects funded by the European Commission: GenomEUtwin (Genome-wide analysis of European twin and population cohorts to identify genes predisposed to common diseases) network of excellence for genomics in Europe ; ENGAGE (European Network for Genetic and Genomic Epidemiology) European network of genetic and genomic epidemiology; CHANCES (Consortium on Health and Aging: Network of Cohorts in Europe and the United States) project aimed at studying the relationships between health and aging and related socio-economic implications.


Currently the MORGAM project participates in the BiomarCaRE consortium (Biomarker for Cardiovascular Risk Assessment in Europe) which studies the value of biomarkers in estimating cardiovascular risk in Europe.

Cohorts involved in the MORGAM project were examined at the baseline (included between 1982 and 2014) and followed over time by the Participating Centers building the follow-up of the cohort. The longest follow-up periods are around 30 years. Each Participating Center has one or more cohorts.


The data of the base line and the follow-up of the Participating Centers are collected in the MORGAM Data Center, where their quality is evaluated and the study database is implemented. Researchers from Participating Centers also propose and participate in data analysis. It is possible to view the map of the geographical distribution of the cohorts participating in the MORGAM project.


The CUORE Project participates in the MORGAM project with the cohorts of Atherosclerotic Diseases Superior Institute of Health (MATISS) and MONICA Latina.




© Istituto Superiore di Sanita (ISS)