The Progetto Cuore – epidemiology and prevention of cardio and 
			cerebrovascular diseases-is coordinated by the “Department of 
			cardiovascular disease, endocrine and metabolic disorders and 
			ageing” of the National health institute (istituto superiore di 
			sanità- Iss).
			 
			The Progetto Cuore was launched in 1998 thanks to a collaboration 
			between four research groups lead by physicians with the same 
			background knowledge (MONICA-Brianza – Prof. Marco Ferrario; 
			MONICA-Friuli – Dott. Diego Vanuzzo; ATENA – Prof. Salvatore Panico; 
			MATISS – Dott.ssa Simona Giampaoli) and thanks to funding of the 
			Ministry of health.
			 
			In the frame of the Progetto Cuore many activities have been 
			performed, thanks to the work done by researchers and technicians of 
			the National Health institute (Iss), to the cooperation with other 
			Italian or foreign research groups, and to the participation to 
			projects funded by the Ministry of Health and the European union. 
			The results of this activities play a very important role for the 
			prevention of cardiovascular diseases in the \adult population:
			
				- development of the risk charts and of a software that allow 
				to evaluate the risk score to predict cardiovascular risk in a 
				easily manner 
 
				- Implementation of a periodical population examination on a 
				national level, which allow to gather many information: degree 
				of study, lifestyle, pathological anamnesis, pharmacological 
				anamnesis, family medical history and a direct, standardized 
				measure of risk factors for chronic diseases
 
				- Creation of a queryable database, CuoreData, which provide 
				the most relevant statistics on the health status of the Italian 
				adult population
 
				- Creation and activation of the National Register of major 
				coronary and cerebrovascular events
 
				- Fulfillment of a biological sample storage connected to a 
				wide population database
 
				- Creation of an educational plan on the evaluation of 
				cardiovascular risk, which has been thought for General 
				Practitioners 
 
				- The study of the etiological role of new risk factors on 
				cardiovascular risk prediction.
 
			
			Since 2005 the Progetto Cuore have been participating to the 
			activities of the National center for disease prevention and control 
			(Centro nazionale per la 
			prevenzione e il controllo delle malattie Ccm), Ministry of 
			health, with many different projects.
			 
			In Italy, the Progetto Cuore collaborates with:
			
				- The National Association of Hospital Cardiologists – (ANMCO) 
				and Health Care Foundation
 
				- National Cancer Institute MilanMonzino Cardiology Center 
				 General Inspectorate for Military Health (Igesan)
 
			
			The Progetto Cuore participates to the following international 
			collaborations, consortia, projects, networks, and joint actions:
			
				- “Action Network on measuring population and organizational 
				health literacy M-POHL”, an international network established 
				under the umbrella of the WHO European Health Information 
				Initiative (EHII) aiming at measuring the level of health 
				literacy in the population and in the management and 
				organization of health systems (network M-POHL)
 
				- “InfAct-Information for Action”, European joint action 
				aiming at setting-up a sustainable and solid infrastructure on 
				EU health information system which supports knowledge, research 
				and health policy
 
				- “European Health Examination Survey (EHES)”, a joint action 
				between EU Countries which organize national health examination 
				surveys  (HES). EHES aims to ensure high quality and 
				comparable results of the surveys
 
				- “Global Burden of Diseases, Injuries, and Risk Factors Study 
				(GBD)”, the most wide and complete project to measure 
				characteristics of epidemiological trends worldwide
 
				- “NCD Risk Factor Collaboration (NCD-RisC)”, a network 
				composed by researchers coming from 200 different Countries, 
				which provide updated data on chronic disease’s risk factors
 
				- “Emerging Risk Factors Collaboration (ERFC)”, a 
				collaborative group which balance data collected over more than 
				30 different Countries to study risk factors and specific cause 
				mortality for cardiovascular diseases
 
				- “BiomarCaRE (Biomarker for Cardiovascular Risk Assessment in 
				Europe)”, an international research project aiming at evaluating 
				biomarkers for prediction of cardiovascular diseases in the 
				European population
 
				- “MORGAM (MOnica Risk, Genetics, Archiving and Monograph) 
				Project”, an international collaborative study which aims at 
				exploring the relationship between cardiovascular diseases, 
				classic and genetic risk factors, and biomarkers
 
				- “European CKD Burden Consortium”, focused on the 
				epidemiologic study of chronic kidney disease